BİYOKİMYA ANABİLİM DALI HAKKINDA          AKADEMİK KADRO          YÜRÜTÜLEN ÇALIŞMALAR          DUYURULAR

KİŞİSEL BİLGİLER          PROJELER          YAYINLAR

YAYINLARI:

ULUSLARARASI MAKALELER

1. Guler S, Zik B, Yalcin A*. Upregulation of dual-specificity phosphatase-26 is required for transforming growth factor beta 1(TGF beta 1)-induced Epithelial-mesenchymal transition in A549 and PANC1 cells. Molecular Biology Reports (2022), DOI : 10.1007/s11033-022-07893-1

2. Guler S, Altunok T, Sarioglu A, Zik B, Asmaz D, Kayapunar N, Sonmez O, Erbaykent Tepedelen B, Yalcin A*. Overexpression of dual-specificity phosphatases 4 and 13 attenuates transforming growth factor β1-induced migration and drug resistance in A549 cells in vitro. Biochem Biophys Res Commun. Volume 606, 2022,Pages 35-41.

3.Ozcan SC, Mutlu A, Altunok TH, Gurpinar Y, Sarioglu A, Guler S, Muchut RJ, Iglesias AA, Celikler S, Campbell PM, Yalcin A*. Simultaneous inhibition of PFKFB3 and GLS1 selectively kills KRAS-transformed pancreatic cells. Biochem Biophys Res Commun. 2021 Sep 24;571:118-124. doi: 10.1016/j.bbrc.2021.07.070. Epub 2021 Jul 26. PMID: 34325126.

4. Ozcan SC, Sarioglu A, Altunok TH, Akkoc A, Guzel S, Guler S, Imbert-Fernandez Y, Muchut RJ, Iglesias AA, Gurpinar Y, Clem AL, Chesney JA, Yalcin A*. PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells. Mol Cell Biochem. 2020 Jul;470(1-2):115-129. doi: 10.1007/s11010-020-03751-5. Epub 2020 May 15. PMID: 32415418.

5. Yalcin A*, Solakoglu TH, Ozcan SC, Guzel S, Peker S, Celikler S, Balaban BD, Sevinc E, Gurpinar Y, Chesney JA. 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase-3 is required for transforming growth factor β1-enhanced invasion of Panc1 cells in vitro. Biochem Biophys Res Commun. 2017 Mar11;484(3):687-693. doi: 10.1016/j.bbrc.2017.01.178.

6. Yalcin A, Clem B, Imbert Fernandez Y, Özcan SC, Peker S, Oneal J, Klarer A, Clem A, Telang S, Chesney J (2014). 6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1 mediated phosphorylation of p27. Cell Death and Disease, 5(7), 1337, Doi:10.1038/cddis.2014.292.

7. Telang S, Nelson KK, Siow DL, Yalcin A,Thornburg JM, Imbert Fernandez Y, Klarer AC, Farghaly H, Clem B, Eaton J,Chesney J (2012). Cytochrome c oxidase is activated by the oncoprotein Ras and is required for A549 lung adenocarcinoma growth. Molecular Cancer, 11(1), 60. Doi: 10.1186/14764598-11-60.

8. Clem B, Clem A, Yalcin A, Goswami U, Arumugam S, Telang S, Trent J, Chesney J (2011). A novel small molecule antagonist of choline kinase that simultaneously suppresses MAPK and PI3K AKT signaling. Oncogene, 30(30), 3370-3380., Doi: 10.1038/onc.2011.51

9. Yalçın E, Temizel EM, Yalcin A, Uzabacı E (2010). Relationship with gamma glutamyl transpherase activity and glutaraldehyde coagulation test of serum immunoglobulin G concentration in newborn goat kids. Small Ruminant Research, 93, 0-0.

10. Yalcin A, Clem B, Simmons A, Lane A, Nelson KK, Clem A, Brock E, Siow D, Wattenberg B, Telang S, Chesney J (2009). Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin dependent kinases. Journal of Biological Chemistry, 284(36), 24223-24232., Doi:10.1074/jbc. M109.016816.

11. Yalcin A, Sucheta T, Brian C, Chesney J (2009). Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatases in cancer. Experimental and Molecular Pathology, 86(3), 174-179., Doi: 10.1016/j.yexmp.2009.01.003.

12. Yalcin A, Clem B, Makoni S, Clem A, Nelson KK, Thornburg J, Siow D, Lane A, Brock E, Guswami U, Eaton J, Telang S, Chesney J (2009). Selective inhibition of choline kinase simultaneously attenuates MAPK and PI3K AKT signaling. Oncogene, 29(1), 139-149., Doi:10.1038/onc.2009.317

13. Clem B, Telang S, Clem A, Yalcin A, Meier J, Simmons A, Rasku MA, Arumugam S, Dean W, Eaton J, Lane A, Trent J, Chesney J (2008). Small molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth. Molecular Cancer Therapeutics, 7(1),0-0., Doi: 10.1158/1535-7163.MCT-07-0482.

14. Telang S, Yalcin A, Clem A, Bucala R, Lane A, Eaton J, Chesney J (2006). Ras transformation requires metabolic control by 6-phosphofructo-2-kinase. Oncogene, 25(55), 7225-7234.

15. Chesney J, Telang S, Yalcin A, Clem A, Wallis N, Buchala R (2005). Targeted disruption of inducible 6-phosphofructo-2-kinase results in embryonic lethality. Biochemical and Biophysical Research Communications, 331(1), 139-146.

16. Polat Ü, Tanrıverdi M, Türkyılmaz Ö, Yalcin A (2004). Reference Serum Protein and Lipoprotein Fractions of Ostriches Struthio camelus. Onderstepoort J. Vet. Res., 71(1):77-9, 2004. PMID:15185578

17. Yalcin A*, Çetin M (2004). Electrophoretic separation of urine proteins of healthy dogs and dogs with nephropathy and detection of some urine proteins of dogs using immunoblotting. Revue De Medecine Veterinaire, 155 (2):104-112,  2004.

18. Cetin, M, Petek M, Polat U, Yalcin A. Effects of dietary carnitine supplementation on plasma carnitine and some serum biochemical parameters in lambs. Revue de Medecine Veterinaire, 154(3): 195-198, 2003.

19. Cetin M, Dogan I, Polat U, Yalcin A, Turkyilmaz O.  Blood biochemical parameters in fertile and repeat breeder cows. Indian J of Animal Sciences, 72(10): 865-866, 2002.

ULUSAL MAKALELER

1.YALÇIN A*., ÇETİN M., Plazma lipoproteinleri ve klinik önemi, U.Ü. Vet. Fak. Derg., 20,123-129, 2001

2.ÇETİN M., POLAT Ü., AK İ., YALÇIN A., Hindilerde sınırlı beslemenin serum metabolit, elektrolit düzeyleri ve canlı ağırlık üzerine etkileri, U.Ü. Vet. Fak. Derg., 20, 1-2, 175-180, 2001.

3.ÇETİN M, DENİZ G, POLAT Ü, YALÇIN A, Broylerlerde İnorganik ve Organik Selenyum İlavesinin Biyokimyasal Kan Parametreleri Üzerine Etkisi, U.Ü. Vet. Fak. Dergisi 21,59-63,2002.

4.POLAT Ü, ÇETİN M, YALÇIN A., Yüksek Verimli Süt İneklerinde Laktasyonun Çeşitli Evrelerinde Kandaki Bazı Biyokimyasal Parametreler ile Süt Verimi Arasındaki İlişkiler, U.Ü. Vet. Fak. Dergisi, 21,65-69,2002.

5.POLAT Ü., YALÇIN A., ÇETİN M., AK İ.,DOĞRUTEKİN D.,  Effects of Feeding With Molasses and Vibrotal On Some Serum Biochemical  Parameters and Liveweight Gains in Lambs, Uludag Univ. J. Fac. Vet. Med., 24, 1-2-3-4: 1-6, 2005.